BDBM50556781 CHEMBL3719364

SMILES O=c1nc(OCC2COCCO2)cc2-c3ccc(OCc4ccccn4)cc3CCn12

InChI Key InChIKey=KSGKMLVYIUJQMZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50556781   

TargetG-protein coupled receptor 84(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556781(CHEMBL3719364)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human GPR84 expressed in CHO-K1 cells assessed as reduction in 6-OAU-induced inhibition of forskolin stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556781(CHEMBL3719364)
Affinity DataIC50: 716nMAssay Description:Antagonist activity at human GPR84 expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in 6-OAU induced intracellular calcium resp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556781(CHEMBL3719364)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human GPR84 expressed in CHO-K1 cells assessed as reduction in 6-OAU induced intracellular cAMP production pretreated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed