BDBM50556779 CHEMBL3715656

SMILES O=c1nc(OCC2COCCO2)cc2-c3ccc(cc3CCn12)C#CCNc1ccccc1

InChI Key InChIKey=YHSONAVIPVCZDX-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50556779   

TargetG-protein coupled receptor 84(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at recombinant human N-terminal epitope tagged/eYFP-fused FLAG-tagged GPR84 expressed in Flp-In TREx 293 cells assessed as inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at recombinant human N-terminal epitope tagged/eYFP-fused FLAG-tagged GPR84 expressed in Flp-In TREx 293 cells assessed as inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at recombinant human N-terminal epitope tagged/eYFP-fused FLAG-tagged GPR84 expressed in Flp-In TREx 293 cells assessed as inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 7.20nMAssay Description:Antagonist activity at human Flag-tagged Gialpha-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as reduction in ZQ-16-induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at human Flag-tagged Gialpha-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as reduction in PSB-16671-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 126nMAssay Description:Antagonist activity at mouse Galphai2-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as reduction in ZQ-16-induced stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at mouse Galphai2-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as reduction in PSB-16671-induced stim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at GPR84 in LPS-treated human THP-1 cell membrane assessed as reduction in ZQ-16-induced stimulation of [35S]GTPgammaS binding pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at GPR84 in LPS-treated human THP-1 cell membrane assessed as reduction in PSB-16671-induced stimulation of [35S]GTPgammaS bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 316nMAssay Description:Antagonist activity at GPR84 in LPS-treated mouse RAW 264.7 cell membrane assessed as reduction in ZQ-16-induced stimulation of [35S]GTPgammaS bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 145nMAssay Description:Antagonist activity at GPR84 in LPS-treated mouse RAW 264.7 cell membrane assessed as reduction in PSB-16671-induced stimulation of [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed