BDBM50555680 CHEMBL4784006

SMILES ONC(=O)c1ccc(CNC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1

InChI Key InChIKey=KMHKOOKREYIIBC-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50555680   

TargetHistone deacetylase 7(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC7 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 11(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length HDAC11 (unknown origin) expressed in insect Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 8(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant full length human HDAC8 expressed in insect Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in insect Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant full length human HDAC3 expressed in insect Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 590nMAssay Description:Inhibition of HDAC6 in human HeLa cells assessed by deacetylation measured after 15 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Zebrafish)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 74nMAssay Description:Inhibition of N-terminal 6 His-SUMO tagged Zebrafish HDAC6 CD2 domain expressed in Escherichia coli BL21(DE3) RILP pretreated for 10 mins before FITC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC10 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Elect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC9 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 215nMAssay Description:Inhibition of recombinant full length human HDAC3 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 5(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC5 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 4(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC4 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC1 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 11(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC11 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Elect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 694nMAssay Description:Inhibition of recombinant full length human HDAC8 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50555680(CHEMBL4784006)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed