BDBM50555577 CHEMBL4787536

SMILES CSc1nnc(-c2ccc(F)cc2)n1-c1ccnc(Nc2cccc(NC(=O)C=C)c2)c1

InChI Key InChIKey=PDWKHLVZXHJEBJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50555577   

TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50555577(CHEMBL4787536)
Affinity DataIC50: 234nMAssay Description:Inhibition of human EGFR cytoplasmic domain L858R/T790M mutant (669 to 1210 residues) expressed in baculovirus infected Sf21 cells using biotin-label...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed