BDBM50554914 CHEMBL4790115::US20240059655, Compound PW0875

SMILES OCCNC(=O)c1cccc2N(CCc12)c1cc(ncn1)C(F)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=SCSCNNZIBRYFAN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50554914   

TargetG-protein coupled receptor 52(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50554914(CHEMBL4790115 | US20240059655, Compound PW0875)
Affinity DataEC50:  557nMAssay Description:Agonist activity at human GPR52 expressed in HEK293 cells assessed as increase in cAMP levels incubated for 15 mins by Glosensor cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 52(Mouse)
University Of Texas

US Patent
LigandPNGBDBM50554914(CHEMBL4790115 | US20240059655, Compound PW0875)
Affinity DataEC50:  557nMAssay Description:In Vitro Evaluation of GPR52 Activation. Newly synthesized compounds were evaluated in a twelve-point concentration-response for GPR52 agonist activi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent