BDBM50554278 CHEMBL4785007

SMILES CC(C)C[C@@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CSCc2ccc(cc2)-c2ccc(CSC[C@H](NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC1=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCCNC(=O)c1ccc3c(c1)C(=O)OC31c3ccc(O)cc3Oc3cc(O)ccc13)C(N)=O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)CN)[C@@H](C)O

InChI Key InChIKey=ASVCCOFSYJQTGW-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50554278   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Tokyo Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50554278(CHEMBL4785007)
Affinity DataKd:  5.29E+4nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Tokyo Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50554278(CHEMBL4785007)
Affinity DataKd:  2.70E+5nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constant in presence of 50 uM p53 peptide by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed