BDBM50554277 CHEMBL4791628

SMILES CSCC[C@@H]1NC(=O)CNC(=O)[C@H](CSCc2ccc(cc2)-c2ccc(CSC[C@H](NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC1=O)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCCNC(=O)c1ccc3c(c1)C(=O)OC31c3ccc(O)cc3Oc3cc(O)ccc13)C(N)=O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)CN

InChI Key InChIKey=GGTPNCASLWUMFK-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50554277   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Tokyo Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50554277(CHEMBL4791628)
Affinity DataKd:  3.10E+4nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed