BDBM50554055 CHEMBL4755252

SMILES Nc1cc([C@H](CCCN2CCC(CC2)c2ccccc2)c2ccccc2)c2nn[nH]c2n1

InChI Key InChIKey=YJFLOKSEQLPJRQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50554055   

TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554055(CHEMBL4755252)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetThyroid peroxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554055(CHEMBL4755252)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of TPO (unknown origin) using 3-iodo tyrosine as substrate incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed