BDBM50553882 CHEMBL4751935

SMILES Oc1ccc(cc1)-n1cc(nn1)-c1ccccn1

InChI Key InChIKey=FWCDFBFRXPYHIG-UHFFFAOYSA-N

Data  4 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50553882   

TargetMacrophage migration inhibitory factor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50553882(CHEMBL4751935)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of C-terminal His-tagged recombinant human MIF tautomerase activity expressed in Escherichia coli BL21 using 4-hydroxyphenyl pyruvic acid ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50553882(CHEMBL4751935)
Affinity DataKd:  4.00E+3nMAssay Description:Displacement of 4'-(7-Hydroxy-2-oxo-2H-chromen-3-yl)-[1,1'-biphenyl]-4-carboxylic acid from C-terminal His-tagged recombinant human MIF expressed in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50553882(CHEMBL4751935)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of C-terminal His-tagged recombinant human MIF tautomerase activity expressed in Escherichia coli BL21 using 4-hydroxyphenyl pyruvic acid ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50553882(CHEMBL4751935)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of C-terminal His-tagged recombinant human MIF tautomerase activity expressed in Escherichia coli BL21 using 4-hydroxyphenyl pyruvic acid ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50553882(CHEMBL4751935)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50553882(CHEMBL4751935)
Affinity DataKi:  8.80E+3nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli using 4-hydroxyphenyl pyruvic acid as substrate preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed