BDBM50552916 CHEMBL4740322

SMILES FC(F)(F)c1nc(no1)-c1ccc(cc1)C(=O)NC1(CN2CCCC2)CC1

InChI Key InChIKey=MTMQPKCXWHSWNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552916   

TargetHistone deacetylase 4(Human)
Charles River Discovery

Curated by ChEMBL
LigandPNGBDBM50552916(CHEMBL4740322)
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC4 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Charles River Discovery

Curated by ChEMBL
LigandPNGBDBM50552916(CHEMBL4740322)
Affinity DataIC50: 180nMAssay Description:Inhibition of Class 2A HDAC4 in human Jurkat E6.1 cells using Boc-Lys-(TFA)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed