BDBM50552908 CHEMBL4753102

SMILES C[C@H](CN1CCC[C@H](C1)OC(F)F)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F

InChI Key InChIKey=YOGWQNKZBZCDFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552908   

TargetHistone deacetylase 4(Human)
Charles River Discovery

Curated by ChEMBL
LigandPNGBDBM50552908(CHEMBL4753102)
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC4 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Charles River Discovery

Curated by ChEMBL
LigandPNGBDBM50552908(CHEMBL4753102)
Affinity DataIC50: 60nMAssay Description:Inhibition of Class 2A HDAC4 in human Jurkat E6.1 cells using Boc-Lys-(TFA)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed