BDBM50552415 CHEMBL4749601

SMILES NC(=O)[C@H](N([C@@H]1CCc2c1cc(Cl)cc2F)C(=O)c1ccccc1)c1ccccc1

InChI Key InChIKey=ZLDDOCXDTRTKDS-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552415   

LigandPNGBDBM50552415(CHEMBL4749601)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50552415(CHEMBL4749601)
Affinity DataEC50:  4.70E+3nMAssay Description:Activation of human PXR ligand binding domain incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed