BDBM50552134 CHEMBL4759149::US11472815, Compound 22

SMILES CNc1ccc(cc1-n1cnc(c1)-c1ccc(cc1O)C(F)(F)F)[N+]([O-])=O

InChI Key InChIKey=NDXRKYCETUZOSA-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50552134   

TargetToll-like receptor 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50552134(CHEMBL4759149 | US11472815, Compound 22)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at TLR2 in HEK-Blue hTLR2 cells assessed as NF-kappaB activation preincubated for 24 hrs followed by replacement of medium containin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM50552134(CHEMBL4759149 | US11472815, Compound 22)
Affinity DataEC50:  4.88nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetToll-like receptor 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50552134(CHEMBL4759149 | US11472815, Compound 22)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed