BDBM50551142 CHEMBL4755929

SMILES Cc1ccc2nc(NC(=O)c3ncn(CC(=O)NCc4ccc5OCOc5c4)n3)[nH]c2c1

InChI Key InChIKey=FPKFIIPMUISEER-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50551142   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551142(CHEMBL4755929)
Affinity DataIC50: 5.56E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed