BDBM50551141 CHEMBL4748970

SMILES Nc1ncnc2n(CCNC(=O)Cn3cnc(n3)C(=O)NC3CCCCC3)ccc12

InChI Key InChIKey=UVRYYFSGHPTPTI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50551141   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551141(CHEMBL4748970)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed