BDBM50551133 CHEMBL4741080

SMILES Cc1ccc(NC(=O)c2ncn(CC(=O)NCCn3cnc4[nH]ccc4c3=O)n2)cc1C

InChI Key InChIKey=YHNTZIOTDIXPEK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50551133   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551133(CHEMBL4741080)
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed