BDBM50550964 CHEMBL4752128

SMILES CNC(=O)c1cncc(c1)-c1cnc(Cl)c(NS(=O)(=O)c2ccccc2)c1

InChI Key InChIKey=IHWSJFBJORCEAK-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50550964   

LigandPNGBDBM50550964(CHEMBL4752128)
Affinity DataIC50: 191nMAssay Description:Inhibition of human PI3Kalpha by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50550964(CHEMBL4752128)
Affinity DataIC50: 392nMAssay Description:Inhibition of human PI3Kbeta by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50550964(CHEMBL4752128)
Affinity DataIC50: 104nMAssay Description:Inhibition of human PI3Kdelta by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50550964(CHEMBL4752128)
Affinity DataIC50: 324nMAssay Description:Inhibition of human PI3Kgamma by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50550964(CHEMBL4752128)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PIK3C2alpha by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50550964(CHEMBL4752128)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PIK3C2beta by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50550964(CHEMBL4752128)
Affinity DataIC50: 681nMAssay Description:Inhibition of human VPS34 by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50550964(CHEMBL4752128)
Affinity DataIC50: 165nMAssay Description:Inhibition of human PI4K3alpha by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50550964(CHEMBL4752128)
Affinity DataIC50: 433nMAssay Description:Inhibition of human PI4K3beta by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed