BDBM50550514 CHEMBL4755146

SMILES O=C(NCCCN1CCCC1)c1cccc(c1)-c1ccccc1N1CCN(CCc2ccccc2)CC1

InChI Key InChIKey=KYBJZXMGLXKKJC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550514   

TargetN-lysine methyltransferase SMYD2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50550514(CHEMBL4755146)
Affinity DataIC50: 339nMAssay Description:Inhibition of SMYD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50550514(CHEMBL4755146)
Affinity DataEC50:  4.91E+3nMAssay Description:Inhibition of SMYD2 (unknown origin) expressed in in human U2OS cells assessed as reduction in monomethylated p53 levels incubated for 24 hrs by immu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed