BDBM50550472 CHEMBL4779399

SMILES CC(C)CCOc1nc(ccc1C(=O)NC1C2CC3CC1CC(O)(C3)C2)N1CC[C@H](CC(O)=O)C1

InChI Key InChIKey=KIKAPQLYTFDOQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50550472   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50550472(CHEMBL4779399)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed