BDBM50549893 CHEMBL4757103

SMILES C[C@@H]1CN(CCN1C(=O)CCCc1cccc2ncccc12)c1ncc(F)cc1C

InChI Key InChIKey=OIZGGNJJLMUGKL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50549893   

TargetMuscarinic acetylcholine receptor M4(Human)
Pipeline Therapeutics

Curated by ChEMBL
LigandPNGBDBM50549893(CHEMBL4757103)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human recombinant muscarinic receptor M4 expressed in CHO-K1 cells assessed as EC80 acetylcholine-induced calcium flux incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pipeline Therapeutics

Curated by ChEMBL
LigandPNGBDBM50549893(CHEMBL4757103)
Affinity DataIC50: 501nMAssay Description:Antagonist activity at human recombinant muscarinic receptor M3 expressed in CHO-K1 cells assessed as EC80 acetylcholine-induced calcium flux incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Pipeline Therapeutics

Curated by ChEMBL
LigandPNGBDBM50549893(CHEMBL4757103)
Affinity DataIC50: 631nMAssay Description:Antagonist activity at human recombinant muscarinic receptor M2 expressed in CHO-K1 cells assessed as EC80 acetylcholine-induced calcium flux incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Pipeline Therapeutics

Curated by ChEMBL
LigandPNGBDBM50549893(CHEMBL4757103)
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity at human recombinant muscarinic receptor M1 expressed in CHO-K1 cells assessed as EC80 acetylcholine-induced calcium flux incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed