BDBM50548985 CHEMBL4792711::US20230303494, Compound 4
SMILES Cc1c(CNc2ccc(CN[C@H](CO)C(O)=O)c(OCc3cccc(c3)C#N)c2)cccc1-c1ccccc1
InChI Key InChIKey=HWLMUXYCTGZUML-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50548985
TargetProgrammed cell death 1 ligand 1(Human)
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
Affinity DataKon: 0.00118M-1s-1Assay Description:Binding affinity to biotinylated human AVI-PD-L1 assessed as dissociation constant by biolayer interferometryMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of PD1-Tag2/PD-L1-Tag1 (unknown origin) protein-protein interaction preincubated for 15 mins followed by addition of anti-Tag1-Eu3+ and an...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
Affinity DataIC50: 1.16E+3nMAssay Description:Example 39: The experimental method and procedure were carried out in accordance with the kit instructions, which were briefly described as follows: ...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
Affinity DataKd: 1.81nMAssay Description:Example 40: In the experiment, the instrument OctectRED of Fortebio Company based on biofilm interferometry (BLI) technology was used to capture huma...More data for this Ligand-Target Pair