BDBM50548685 CHEMBL4776820

SMILES O=c1[nH]c(cc2ncccc12)C1=C[C@@H](CC1)N1CCN(CC1)c1ccc(cc1)C#N

InChI Key InChIKey=IBBZXRLLZKUNIM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50548685   

TargetPoly [ADP-ribose] polymerase 1(Human)
Lupin

Curated by ChEMBL
LigandPNGBDBM50548685(CHEMBL4776820)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Lupin

Curated by ChEMBL
LigandPNGBDBM50548685(CHEMBL4776820)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50548685(CHEMBL4776820)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of PARP3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50548685(CHEMBL4776820)
Affinity DataIC50: 769nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50548685(CHEMBL4776820)
Affinity DataIC50: 74nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed