BDBM50548108 CHEMBL4749745

SMILES COc1cc2ncc(C(=O)N(C)C)c(Nc3ccc(Cl)cc3F)c2cc1OC

InChI Key InChIKey=GQMSZQRRWWHXPQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548108   

LigandPNGBDBM50548108(CHEMBL4749745)
Affinity DataEC50:  950nMAssay Description:Binding affinity to MTH1 in human K562 cells assessed as thermal stabilization preincubated for 30 mins followed by heating at 52 degree C for 3 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50548108(CHEMBL4749745)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed