BDBM50548085 CHEMBL4792279

SMILES Cc1nn(-c2ccc(F)cc2)c2ncnc(Nc3ccc(F)c(Cl)c3)c12

InChI Key InChIKey=RSNDESFUJYJZCD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50548085   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50548085(CHEMBL4792279)
Affinity DataIC50: 254nMAssay Description:Inhibition of human HER2 using Biotin- FLT3 (Tyr589) peptide as substrate preincubated for 5 mins followed by ATP/substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50548085(CHEMBL4792279)
Affinity DataIC50: 186nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50548085(CHEMBL4792279)
Affinity DataIC50: 186nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 30 mins in presence of ATP by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50548085(CHEMBL4792279)
Affinity DataIC50: 254nMAssay Description:Inhibition of HER2 (unknown origin) preincubated for 5 mins followed by substrate peptide and ATP addition measured after 30 mins by horseradish pero...More data for this Ligand-Target Pair
In DepthDetails
PubMed