BDBM50547859 CHEMBL4752708

SMILES Cc1[nH]c(C(=O)Nc2nc3ccc(NC(=O)C(O)=O)cc3s2)c(Cl)c1Cl

InChI Key InChIKey=GBQZRFCGAJTKDG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50547859   

TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50547859(CHEMBL4752708)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50547859(CHEMBL4752708)
Affinity DataIC50: 38nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50547859(CHEMBL4752708)
Affinity DataIC50: 290nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50547859(CHEMBL4752708)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50547859(CHEMBL4752708)
Affinity DataIC50: 38nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed