BDBM50547499 CHEMBL4785454

SMILES CC(C)C(=O)c1c(Cc2cccc(c2)\N=N\c2ccc3c(cc(c(N)c3c2O)S(O)(=O)=O)S(O)(=O)=O)nn2ccccc12

InChI Key InChIKey=DDUSPQQMFMSMNK-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50547499   

TargetMacrophage migration inhibitory factor(Human)
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50547499(CHEMBL4785454)
Affinity DataKd:  6.86E+3nMAssay Description:Binding affinity to recombinant biotinylated human MIF expressed in Escherichia coli BL21 DE3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50547499(CHEMBL4785454)
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of recombinant biotinylated human MIF tautomerase activity expressed in Escherichia coli BL21 DE3 assessed as reduction in tautomerization...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50547499(CHEMBL4785454)
Affinity DataIC50: 930nMAssay Description:Inhibition of recombinant human MIF expressed in Escherichia coli BL21 DE3 binding to recombinant soluble human CD74 receptor ectodomain (73 to 232 r...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50547499(CHEMBL4785454)
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of MIF-induced IL-8 secretion in human foreskin fibroblasts incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed