BDBM50547201 CHEMBL4792343

SMILES COc1ccc(cc1Cl)N(C(C(=O)NCCc1ccccc1)c1cccs1)C(=O)C#C

InChI Key InChIKey=QPLSTCRVOIXXRB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547201   

TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50547201(CHEMBL4792343)
Affinity DataEC50:  150nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50547201(CHEMBL4792343)
Affinity DataEC50:  1.98E+4nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed