BDBM50546612 CHEMBL4753907

SMILES CC(C)n1ncc2CC3(CCN(CC3)C(=O)c3cc(nc(c3)-c3ccc(cc3)C(O)=O)N(C)C)CC(=O)c12

InChI Key InChIKey=NMUDXSTWPJFVCN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50546612   

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50546612(CHEMBL4753907)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of recombinant human ACC2 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50546612(CHEMBL4753907)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of recombinant human ACC2 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50546612(CHEMBL4753907)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of recombinant human ACC1 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50546612(CHEMBL4753907)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of recombinant human ACC1 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed