BDBM50546216 CHEMBL4745519

SMILES C[C@@H]1OCC2(CCC(CC2)c2cnc3nc(Sc4ccnc(N5CCCC5)c4Cl)ccc3n2)[C@@H]1N

InChI Key InChIKey=GPXXQOPZQAAQMF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50546216   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546216(CHEMBL4745519)
Affinity DataIC50: 100nMAssay Description:Allosteric inhibition of full-length His6-tagged human SHP2 (2 to 527 residues) expressed in Escherichia coli using DiFMUP as substrate in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed