BDBM50545815 CHEMBL4632533

SMILES CC(C)c1onc(c1COc1ccc(COc2ccc(CC(O)=O)cc2)c(Cl)c1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=WTQWEADBWYWOHV-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50545815   

TargetBile acid receptor(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50545815(CHEMBL4632533)
Affinity DataEC50:  800nMAssay Description:Activation of human FXR LBD expressed in HEK293T cells assessed as induction of receptor activation incubated for 12 to 14 hrs by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50545815(CHEMBL4632533)
Affinity DataEC50:  1.80E+3nMAssay Description:Activation of human PPAR-delta LBD expressed in HEK293T cells assessed as induction of receptor activation incubated for 12 to 14 hrs by luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50545815(CHEMBL4632533)
Affinity DataEC50:  800nMAssay Description:Agonist activity at FXR in human HeLa cells incubated for 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50545815(CHEMBL4632533)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human PPARdelta expressed in HEK293T cells incubated for 12 to 14 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed