BDBM50544222 CHEMBL4646763

SMILES COc1nc2ccccc2cc1-c1cnc([nH]1)[C@@H](N)CCCCCC(=O)c1ncc(CO)o1

InChI Key InChIKey=BMEYTXZHJHHKPN-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50544222   

TargetHistone deacetylase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50544222(CHEMBL4646763)
Affinity DataIC50: 194nMAssay Description:Inhibition of full length human recombinant FLAG-tagged HDAC1 expressed in HEK293F cells using FLUOR DE LYS as substrate preincubated for 3 hrs follo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50544222(CHEMBL4646763)
Affinity DataIC50: 470nMAssay Description:Inhibition of full length human recombinant FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 cells using FLUOR DE LYS as substrate preincubate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor corepressor 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50544222(CHEMBL4646763)
Affinity DataIC50: 120nMAssay Description:Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50544222(CHEMBL4646763)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of class 1 HDAC in human Jurkat model of HIV latency assessed as reactivation of HIV latency incubated for 20 hrs in presence of 5% NHS by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed