BDBM50544111 CHEMBL4638054

SMILES OC(=O)c1ccc(\C=C\C(=O)c2cccc(c2)[N+]([O-])=O)cc1

InChI Key InChIKey=MHIVVIRGAGOSGU-UHFFFAOYSA-N

Data  6 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50544111   

TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50544111(CHEMBL4638054)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of LYP (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 12(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50544111(CHEMBL4638054)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of PTP-PEST (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50544111(CHEMBL4638054)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50544111(CHEMBL4638054)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50544111(CHEMBL4638054)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50544111(CHEMBL4638054)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Yersinia enterocolitica YopHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50544111(CHEMBL4638054)
Affinity DataKi:  400nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis PtpB assessed as inhibition constant using varying level of pNPP as substrate by Lineweaver-Burk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50544111(CHEMBL4638054)
Affinity DataKi:  800nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis PtpA assessed as inhibition constant using varying level of pNPP as substrate by Lineweaver-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 12(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50544111(CHEMBL4638054)
Affinity DataKi:  1.00E+3nMAssay Description:Competitive inhibition of PTP-PEST (unknown origin) assessed as inhibition constant using varying level of pNPP as substrate by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50544111(CHEMBL4638054)
Affinity DataKi:  1.00E+3nMAssay Description:Non-competitive inhibition of Yersinia enterocolitica YopH assessed as inhibition constant using varying level of pNPP as substrate by Lineweaver-Bur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50544111(CHEMBL4638054)
Affinity DataKi:  1.40E+3nMAssay Description:Non-competitive inhibition of human PTP1B assessed as inhibition constant using varying level of pNPP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50544111(CHEMBL4638054)
Affinity DataKi:  1.90E+3nMAssay Description:Competitive inhibition of LYP (unknown origin) assessed as inhibition constant using varying level of pNPP as substrate by Lineweaver-Burk plot analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed