BDBM50544033 CHEMBL4632854

SMILES CC(C)c1onc(c1COc1ccc(cc1)-c1nc2cc(ccc2n1C)C(O)=O)-c1c(Cl)cccc1Cl

InChI Key InChIKey=KGWSPIGKIWEXQN-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50544033   

TargetVitamin D3 receptor(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50544033(CHEMBL4632854)
Affinity DataIC50: 4.41E+3nMAssay Description:Antagonist activity at human VDR transfected in HEK293T cells measured after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile acid receptor(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50544033(CHEMBL4632854)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human FXR expressed in human HuH7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile acid receptor(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50544033(CHEMBL4632854)
Affinity DataEC50:  64nMAssay Description:Agonist activity at human FXR by lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed