BDBM50543968 CHEMBL4636079

SMILES C[C@@H](Cc1nc2n(ncc2c(=O)[nH]1)-c1ccccc1Cl)C(F)(F)F

InChI Key InChIKey=FFPXPXOAFQCNBS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50543968   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50543968(CHEMBL4636079)
Affinity DataIC50: 55nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Mouse)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50543968(CHEMBL4636079)
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse PDE9A expressed in baculovirus infected Sf9 insect cells using 3[H]-cGMP as substrate incubated for 60 mins by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed