BDBM50543937 CHEMBL4642850

SMILES FC(F)(F)c1ccc(cc1)-n1ccc2cc(ccc12)C(=O)N1CC(C1)N1CCN(CC1)C(=O)c1ccccc1

InChI Key InChIKey=NCZXJSMDSSULMY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50543937   

TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543937(CHEMBL4642850)
Affinity DataIC50: 20nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed