BDBM50543600 CHEMBL4639853

SMILES Cc1cc(Nc2cc(Cl)nc(Oc3ccc(cc3)[N+]([O-])=O)n2)n[nH]1

InChI Key InChIKey=CEUMAXLRGBKFQP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50543600   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543600(CHEMBL4639853)
Affinity DataIC50: 40nMAssay Description:Inhibition of Vps34 in human MCF7-LC3 cells assessed as rapamycin-induced autophagyMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543600(CHEMBL4639853)
Affinity DataIC50: 90nMAssay Description:Inhibition of Vps34 in human MCF7-LC3 cells assessed as starvation-induced autophagyMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543600(CHEMBL4639853)
Affinity DataIC50: 19nMAssay Description:Inhibition of Vps34 in human MCF7-LC3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Technical University Dortmund

Curated by ChEMBL
LigandPNGBDBM50543600(CHEMBL4639853)
Affinity DataIC50: 2nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543600(CHEMBL4639853)
Affinity DataIC50: 19nMAssay Description:Inhibition of VPS34 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed