BDBM50542979 CHEMBL4638536

SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)c(CNC(C)(CO)C(O)=O)cc2Cl)cccc1-c1cnc2ccccc2n1

InChI Key InChIKey=KJGBSKXWCFJEDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50542979   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542979(CHEMBL4638536)
Affinity DataIC50: 119nMAssay Description:Inhibition of human C-terminal Ig-Fc-tagged PD1 (Leu25 to Gln167 residues) expressed in HEK293 cells/human C-terminal epitope-His-tagged PDL1 (Phe19 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50542979(CHEMBL4638536)
Affinity DataIC50: 119nMAssay Description:Inhibition of recombinant human C-terminal IG-tagged PD1 (25 to 167 residues) to human C-terminal His-tagged PD-L1 (18 to 239 residues) protein-prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed