BDBM50542817 CHEMBL4633204

SMILES NC(=N)Nc1ccc(CNC(=O)[C@@H](NC(=O)c2ccc(cc2)-c2ccccc2)c2ccc(OCc3ccccc3)cc2)cc1

InChI Key InChIKey=YPAWTFLZVWWQCQ-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50542817   

TargetGenome polyprotein(DENV-2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50542817(CHEMBL4633204)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Ty...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50542817(CHEMBL4633204)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50542817(CHEMBL4633204)
Affinity DataEC50:  7.60E+3nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease transfected in human HeLa cells measured after 24 hrs by Renilla-luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTrypsin(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50542817(CHEMBL4633204)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of trypsin (unknown origin) using Boc-Val-Pro-Arg-AMC as substrate preincubated for 15 mins followed by substrate addition and measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed