BDBM50542668 CHEMBL4645289

SMILES COc1ccc(cc1OC)N2c3ccncc3N(C2=O)Cc4cc5cc(ccc5n4CCCC#N)Cl

InChI Key InChIKey=BVLCQPKSGBJPGE-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50542668   

TargetFusion glycoprotein F0(Human respiratory syncytial virus)
Janssen Pharmaceutical Companies of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50542668(CHEMBL4645289)
Affinity DataEC50:  0.100nMAssay Description:Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)