BDBM50540496 CHEMBL4635138

SMILES CCSSc1nc2ccccc2s1

InChI Key InChIKey=JJOOBYVUSPDHJX-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50540496   

TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of wild-type full-length human liver FBPase expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malach...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human liver FBPase C38S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 980nMAssay Description:Inhibition of human liver FBPase C92S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human liver FBPase C116S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human liver FBPase C128S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human liver FBPase C179S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human liver FBPase C183S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human liver FBPase C281S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of wild-type full-length human liver FBPase expressed in Escherichia coli BL21 (DE3) using FBP as substrate by malachite green dye based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed