BDBM50540272 (+)-Malbrancheamide::CHEMBL508749

SMILES [H][C@@]12C[C@]34CCCN3C[C@@]1(Cc1c([nH]c3cc(Cl)c(Cl)cc13)C2(C)C)NC4=O

InChI Key InChIKey=GZGGCZADGIBRHT-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540272   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of North Carolina Greensboro

Curated by ChEMBL
LigandPNGBDBM50540272((+)-Malbrancheamide | CHEMBL508749)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21 (DE3) cells using PNPP as substate preincubated for 5 mins followed by substrate additon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed