BDBM50540081 CHEMBL4438921

SMILES Fc1cc2c(cc1N1CCNCC1)n(cc(C(=O)N\N=C\c1ccc3OCOc3c1)c2=O)C1CC1

InChI Key InChIKey=ZOPWVCIVTWGJQR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50540081   

TargetCaspase-3(Human)
Qilu University of Technology (Shandong Academy of Sciences)

Curated by ChEMBL
LigandPNGBDBM50540081(CHEMBL4438921)
Affinity DataIC50: 3.00E+3nMAssay Description:Activation of caspase 3 in human SMMC7721 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCaspase-9(Human)
Qilu University of Technology (Shandong Academy of Sciences)

Curated by ChEMBL
LigandPNGBDBM50540081(CHEMBL4438921)
Affinity DataIC50: 3.00E+3nMAssay Description:Activation of caspase 9 in human SMMC7721 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetApoptosis regulator BAX(Human)
Qilu University of Technology (Shandong Academy of Sciences)

Curated by ChEMBL
LigandPNGBDBM50540081(CHEMBL4438921)
Affinity DataIC50: 3.00E+3nMAssay Description:Activation of Bax in human SMMC7721 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCellular tumor antigen p53(Human)
Qilu University of Technology (Shandong Academy of Sciences)

Curated by ChEMBL
LigandPNGBDBM50540081(CHEMBL4438921)
Affinity DataIC50: 3.00E+3nMAssay Description:Activation of p53 in human SMMC7721 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed