BDBM50540060 CHEMBL4632578

SMILES Nc1cc(cc(c1)C(=O)Nc1cccc(c1)C(=O)Nc1ccc(c2cc(cc(c12)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O)C(=O)Nc1cccc(c1)C(=O)Nc1ccc(c2cc(cc(c12)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O

InChI Key InChIKey=ZNYGLXKSEREWKM-UHFFFAOYSA-H

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50540060   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50540060(CHEMBL4632578)
Affinity DataIC50: 93nMAssay Description:Inhibition of sirtuin 1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50540060(CHEMBL4632578)
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibition of sirtuin 2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50540060(CHEMBL4632578)
Affinity DataIC50: 9.30E+4nMAssay Description:Inhibition of N-terminal GST-tagged human SIRT1 using ZMAL as substrate incubated for 4 hrs in presence of NAD+ by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50540060(CHEMBL4632578)
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibition of N-terminal GST-tagged human SIRT2 using ZMAL as substrate incubated for 4 hrs in presence of NAD+ by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed