BDBM50539863 CHEMBL4636750

SMILES Cc1cn([C@H]2C[C@@H]([C@@H](CO)O2)n2cc(CNc3ccc(cc3)S(N)(=O)=O)nn2)c(=O)[nH]c1=O

InChI Key InChIKey=JHJCKCYGIJXIQG-UHFFFAOYSA-N

Data  7 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50539863   

TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50539863(CHEMBL4636750)
Affinity DataKi:  33nMAssay Description:Inhibition of human CA2 pre-incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50539863(CHEMBL4636750)
Affinity DataKi:  53nMAssay Description:Inhibition of human CA5B pre-incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50539863(CHEMBL4636750)
Affinity DataKi:  65nMAssay Description:Inhibition of human CA5A pre-incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50539863(CHEMBL4636750)
Affinity DataKi:  74nMAssay Description:Inhibition of human CA12 pre-incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50539863(CHEMBL4636750)
Affinity DataKi:  330nMAssay Description:Inhibition of human CA7 pre-incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50539863(CHEMBL4636750)
Affinity DataKi:  489nMAssay Description:Inhibition of human CA9 pre-incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50539863(CHEMBL4636750)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human CA1 pre-incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed