BDBM50539783 CHEMBL4637788

SMILES Cc1cc2-c3ccc(O)cc3O[C@@]3(Oc4cc(cc(O)c4-c(c1)c23)-c1cc2ccc(O)cc2o1)c1ccc(O)cc1O

InChI Key InChIKey=SMHBZVSVLIBGGO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50539783   

TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50539783(CHEMBL4637788)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of SERCA1 in NewZealand rabbit skeletal muscle SR vesicles using ATP as substrate incubated for 2 mins followed by Ca2+ addition by NADH c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rat)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50539783(CHEMBL4637788)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed