BDBM50539608 CHEMBL4646266

SMILES ONC(=O)\C=C\c1ccc2cc(Oc3ccc(cc3)[N+]([O-])=O)ccc2n1

InChI Key InChIKey=QMKQQRSNQKDANL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50539608   

TargetHistone deacetylase 8(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50539608(CHEMBL4646266)
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC8 (1 to 377 residues) expressed in insect cells using RHK-K(Ac)-AMC as substrate measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50539608(CHEMBL4646266)
Affinity DataIC50: 51nMAssay Description:Inhibition of human HDAC6 using fluorogenic-(RHKKAc) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50539608(CHEMBL4646266)
Affinity DataIC50: 6.05E+3nMAssay Description:Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in Sf21 insect cells by using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed