BDBM50539516 CHEMBL4646426

SMILES CCOC(=O)Cc1nn(CNC(=O)CCCN2CCN(CC2)c2cccc(C)c2C)c(=O)c2cc(F)ccc12

InChI Key InChIKey=XFZRXHPMALBAIJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50539516   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50539516(CHEMBL4646426)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]astemizole from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50539516(CHEMBL4646426)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50539516(CHEMBL4646426)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50539516(CHEMBL4646426)
Affinity DataIC50: 123nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin) by cell based radioligand competitive binding analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50539516(CHEMBL4646426)
Affinity DataIC50: 92nMAssay Description:Displacement of [3H]mesulergine from 5-HT2C receptor (unknown origin) by cell based radioligand competitive binding analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50539516(CHEMBL4646426)
Affinity DataIC50: 115nMAssay Description:Displacement of [3H]imipramine from SERT receptor (unknown origin) by cell based radioligand competitive binding analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed