BDBM50538575 CHEMBL4638458

SMILES C[C@H]1CNC[C@H](C)N1Cc1c(C)cc(Cl)cc1-c1ccnc2cc(CN3C(=O)CCC3=O)sc12

InChI Key InChIKey=ZPKJNNBGFQUARW-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50538575   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50538575(CHEMBL4638458)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of recombinant full length USP7 (unknown origin) using ubiquintin-rhodamine as substrate preincubated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50538575(CHEMBL4638458)
Affinity DataEC50:  60nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50538575(CHEMBL4638458)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed