BDBM50538390 CHEMBL4638542

SMILES COCCN1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1

InChI Key InChIKey=JMDDXCKPMOKCEA-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50538390   

TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
Kadmon

Curated by ChEMBL

LigandBDBM50538390(CHEMBL4638542)Copy SMILESCopy InChI

Affinity DataIC50: 143nMAssay Description:Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/11/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetSolute carrier family 2, facilitated glucose transporter member 3(Human)
Kadmon

Curated by ChEMBL

LigandBDBM50538390(CHEMBL4638542)Copy SMILESCopy InChI

Affinity DataIC50: 175nMAssay Description:Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/11/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL