BDBM50538386 CHEMBL4647401

SMILES CC1(CC1)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CCC1

InChI Key InChIKey=IXZVJTRRPOHKJF-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50538386   

TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
Kadmon

Curated by ChEMBL

LigandBDBM50538386(CHEMBL4647401)Copy SMILESCopy InChI

Affinity DataIC50: 242nMAssay Description:Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
8/11/2021
Entry Details Article
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TargetSolute carrier family 2, facilitated glucose transporter member 3(Human)
Kadmon

Curated by ChEMBL

LigandBDBM50538386(CHEMBL4647401)Copy SMILESCopy InChI

Affinity DataIC50: 179nMAssay Description:Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
8/11/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Kadmon

Curated by ChEMBL

LigandBDBM50538386(CHEMBL4647401)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG by manual patch clamp assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
8/11/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL